Consider the following translation:
His laziness disgusts me.
Me da asco su flojedad.
What if I wanted to add "to no end" to the sentence?
His laziness disgusts me to no end.
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There isn't exactly a perfect translation for this because it is an expression, a very colloquial one at that.
You're best choices for communicating the same expression would be:
Su flojera me disgusta ...